人类

CALR - Calreticulin

Alias:
RO
CRT
SSA
cC1qR
HEL-S-99n
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
钙网蛋白是一种高度保守的分子伴侣蛋白,主要存在于内质网中,参与多种细胞过程,包括细胞粘附。此外,它还在蛋白质折叠质量控制和钙稳态中发挥作用。钙网蛋白也在细胞核中被发现,提示它可能参与转录调节。系统性红斑狼疮与针对钙网蛋白的自身抗体滴度增加有关。钙网蛋白的复发突变与多种肿瘤有关,包括骨髓增殖型。[RefSeq,2020年5月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
9
5881 bp
48.14
36
4
8
37

CALR Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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