人类

FBXL18 - F-box And Leucine Rich Repeat Protein 18

Alias:
Fbl18
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一个含有大约40个氨基酸F箱主题的蛋白质家族的成员。这个主题与SKP1相互作用并针对某些蛋白质进行降解非常重要。已表明所编码的蛋白质通过将其靶向多泛素化和蛋白酶体降解来控制FBXL7蛋白的细胞水平,该蛋白通过诱导有丝分裂停止来诱导细胞周期停滞。F箱蛋白质家族的成员,如FBXL18,以其大约40个氨基酸的F箱主题而著称。F箱蛋白通过F箱与SKP1相互作用,并通过其他蛋白质相互作用结构域与泛素化靶标相互作用。[RefSeq,2016年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6
5
59385 bp
78.92
30
--
2
4

FBXL18 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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