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中文人类
TLE6 - TLE Family Member 6, Subcortical Maternal Complex Member
Alias:
GRG6
PREMBL
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这个基因编码一个Groucho/transducin-like Enhancer of split家族成员，该家族是转录共抑制子。编码的蛋白质是哺乳动物皮层下母系复合物的组成部分，该复合物对于植入前发育是必需的。在鼠中，这个基因的敲除导致切割阶段胚胎停育，原因是细胞质F-肌动蛋白网状结构形成缺陷和不对称细胞分裂。在人类中，这个基因的一个等位基因变异与植入前胚胎致死性有关。可变剪接导致多个转录变异体。[由RefSeq，2016年9月提供]
Basic Information
NCBI
Transcripts
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TLE6 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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