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中文人类
SNIP1 - Smad Nuclear Interacting Protein 1
Alias:
PML1
PMRED
NEDHCS
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这个基因编码一个含有螺旋-螺旋结构域和C末端叉头相关（FHA）域的蛋白质。编码的蛋白质作为转录共激活剂，增加c-Myc活性并抑制转化生长因子β（TGF-β）和核因子κB（NF-κB）信号通路。编码的蛋白质还调节周期蛋白D1mRNA的稳定性，可能在细胞增殖和癌症进展中发挥作用。这个基因的突变是精神运动迟缓、癫痫和颅面畸形（PMRED）的原因。[由RefSeq提供，2012年3月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SNIP1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
