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中文人类
BIRC7 - Baculoviral IAP Repeat Containing 7
Alias:
KIAP
LIVIN
MLIAP
RNF50
ML-IAP
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这个基因编码凋亡蛋白抑制家族的一员，并包含一个杆状病毒IAP重复序列（BIR）和一个RING型锌指结构域。BIR结构域对抑制活性至关重要，并与caspases相互作用，而RING指结构域有时增强抗凋亡活性，但并不能单独抑制凋亡。编码的蛋白质水平升高可能与癌症进展有关，并在化疗敏感性中发挥作用。可变剪接产生多种转录子变异体[由RefSeq，2013年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BIRC7 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
