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中文人类
KREMEN2 - Kringle Containing Transmembrane Protein 2
Alias:
KRM2
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这个基因编码一种高亲和力Dickkopf同源1(DKK1)跨膜受体。在鼠类中类似的蛋白质与DKK1相互作用，阻断Wingless(WNT)/beta-catenin信号通路。编码的蛋白质与DKK1和WNT受体脂蛋白相关蛋白6(LRP6)形成三元膜复合物，并诱导LRP6从质膜上的快速内吞和去除。它包含胞外kringle、WSC和CUB结构域。已经观察到这个基因的替代剪接转录变异体编码不同的异构体。[由RefSeq提供，2011年12月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
KREMEN2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
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Score
Related Mouse Models
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Name
MGI
Strain of Origin
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CAS Number
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References Literature
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