大鼠

Cyba - cytochrome b-245 alpha chain

Alias:
Phox
p22-phox
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
参与生成超氧阴离子(O2-)的NAD(P)H氧化酶活性。参与几个过程,包括细胞对伽马辐射的反应;细胞对有机氮化合物的反应;以及正向调控细胞群体增殖。位于几个细胞组件中,包括顶浆膜、焦点粘附和应力纤维。是NADPH氧化酶复合物的一部分。与核周内质网共定位。用于研究高血压和肺高血压。糖尿病视网膜病变、终末期肾脏病、高血压和心肌梗死的生物标志物。该基因的人类同源物涉及动脉疾病(多种)、哮喘、慢性阻塞性肺病和吞噬细胞杀菌功能异常(多种)。与人类CYBA(细胞色素b-245α链)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
6
8072 bp
20.75
8
3

Cyba Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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