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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Cyba - cytochrome b-245 alpha chain
Alias:
Phox
p22-phox
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
参与生成超氧阴离子(O2-)的NAD(P)H氧化酶活性。参与几个过程,包括细胞对伽马辐射的反应;细胞对有机氮化合物的反应;以及正向调控细胞群体增殖。位于几个细胞组件中,包括顶浆膜、焦点粘附和应力纤维。是NADPH氧化酶复合物的一部分。与核周内质网共定位。用于研究高血压和肺高血压。糖尿病视网膜病变、终末期肾脏病、高血压和心肌梗死的生物标志物。该基因的人类同源物涉及动脉疾病(多种)、哮喘、慢性阻塞性肺病和吞噬细胞杀菌功能异常(多种)。与人类CYBA(细胞色素b-245α链)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:79129
ENSEMBL:ENSRNOG00000013014
UNIPROT:Q62737
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
79129
1
6
8072 bp
20.75
8
3
Cyba Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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