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中文大鼠
Apex1 - apurinic/apyrimidinic endodeoxyribonuclease 1
Alias:
APE
Apex
REF-1
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激活NF-kappaB结合活性并具有内切核酸酶活性。参与几个过程，包括细胞对有机氮化合物的反应；负调控平滑肌细胞迁移；以及正向调控有丝分裂细胞周期的G1/S过渡。位于线粒体和细胞核中。是转录调节复合物的一部分。脑缺血；肺疾病；癫痫状态；以及视觉癫痫的生物标志物。这个基因的人类同源物与乳腺癌；女性生殖器官癌症（多种）；脊柱裂；和膀胱癌有关。与人类的APEX1（脱氧核糖核酸糖苷酶1）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Apex1 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
