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中文人类
FTO - FTO Alpha-ketoglutarate Dependent Dioxygenase
Alias:
GDFD
ALKBH9
BMIQ14
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这是一种与AlkB相关的核蛋白，非血红素和2-氧代戊二酸依赖的氧合酶超家族，但该基因的确切生理功能尚不清楚。其他非血红素酶通过氧化脱甲基作用逆转烷基化DNA和RNA损伤。在小鼠和人类中的研究表明，它在神经系统和心血管系统中发挥作用，并与身体质量指数、肥胖风险和2型糖尿病有很强的关联。[由RefSeq，2011年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
FTO Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
