Log In|Sign Up
中文人类
CXCR4 - C-X-C Motif Chemokine Receptor 4
Alias:
FB22
HM89
LAP3
LCR1
NPYR
WHIM
CD184
LAP-3
LESTR
NPY3R
NPYRL
WHIMS
HSY3RR
NPYY3R
WHIMS1
D2S201E
Favorite
这个基因编码一个特异性的CXC趋化因子受体，可以识别基质细胞衍生因子-1。这个蛋白质有7个跨膜区域，位于细胞表面。它和CD4蛋白质一起作用，支持HIV进入细胞，并且在乳腺癌细胞中高表达。这个基因的突变与WHIM（疣，低丙种球蛋白血症，感染，和骨髓发育异常）综合症有关。其他的转录剪接变异体，编码不同的异构体，已经被表征。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CXCR4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
