人类

IL1R2 - Interleukin 1 Receptor Type 2

Alias:
IL1RB
CD121b
IL1R2c
CDw121b
IL-1R-2
IL-1RT2
IL-1RT-2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种属于白细胞介素1受体家族的细胞因子受体。这个蛋白质结合白细胞介素α(IL1A)、白细胞介素β(IL1B)和白介素1受体类型I(IL1R1/IL1RA),并作为诱饵受体,抑制其配体的活性。白细胞介素4(IL4)被报道可以通过诱导这个细胞因子的表达和释放,拮抗白细胞介素1的活性。这个基因和另外三个基因在染色体2q12上形成一个细胞因子受体基因簇。可变剪接导致多个转录变异体和蛋白质异构体。可变剪接产生了膜结合和可溶性的两种蛋白质。可溶性的蛋白质也是通过蛋白水解切割产生的。[由RefSeq提供,2012年5月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10
9
36585 bp
45.42
18
--
8
11

IL1R2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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