Log In|Sign Up
中文人类
LRP8 - LDL Receptor Related Protein 8
Alias:
MCI1
LRP-8
APOER2
HSZ75190
Favorite
这个基因编码低密度脂蛋白受体（LDLR）家族的一员。低密度脂蛋白受体是细胞表面蛋白质，在信号传导和受体介导的特定配体的内吞作用中发挥作用，以便在溶酶体中降解。编码的蛋白质在发育过程中在神经元的迁移中扮演关键角色，通过调节Reelin信号传导，同时也作为胆固醇运输蛋白载脂蛋白E的受体。这个基因的表达可能是重度抑郁症的标志。已经观察到这个基因的替代剪接转录变异体编码多种异构体。[RefSeq,2011年6月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LRP8 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
