人类

ZYX - Zyxin

Alias:
ESP-2
HED-2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
聚焦粘附是使细胞能够粘附到细胞外基质上的肌动蛋白丰富的结构,并且涉及信号转导的蛋白质复合体在此处组装。Zyxin 是一种锌结合磷酸蛋白,它集中在聚焦粘附处和肌动蛋白细胞骨架上。Zyxin 在其 C-端半部分具有一个 N-端富脯氨酸结构域和三个 LIM 结构域。富脯氨酸结构域可能与涉及信号转导途径的蛋白质的 SH3 结构域相互作用,而 LIM 结构域可能涉及蛋白质-蛋白质结合。Zyxin 可以作为信号转导途径中的信使,该途径调节粘附刺激下的基因表达变化,并可能调节肌动蛋白束的细胞骨架组织。可变剪接产生编码相同异构体的多种转录变异体。[由 RefSeq,2008 年 7 月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
10
9767 bp
61.28
34
--
4
29

ZYX Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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