Crebrf - CREB3 regulatory factor

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within maternal behavior; negative regulation of glucocorticoid mediated signaling pathway; and positive regulation of prolactin signaling pathway. Located in nuclear body. Is expressed in blastocyst; early embryo; polar body; and uterus. Orthologous to human CREBRF (CREB3 regulatory factor). [provided by Alliance of Genome Resources, Apr 2022]