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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Il33 - interleukin 33
Alias:
Il-33
Il1f11
NF-HEV
9230117N10Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
能够激活细胞因子活性并参与白细胞介素-33受体的结合。涉及几个过程,包括白细胞介素-33介导的信号通路;参与免疫应答的小胶质细胞激活;以及基因表达调控。在几个过程的上游或内部发挥作用,包括负调控巨噬细胞增殖;正调控细胞防御应答;以及正调控大分子代谢过程。位于细胞核中。在几个结构中表达,包括肾上腺;消化系统;生殖泌尿系统;神经系统;和感觉器官。用于研究阿尔茨海默病。该基因的人类同源物与念珠菌感染;炎症性肠病;和消化性溃疡疾病有关。与人类IL33(白细胞介素33)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:77125
ENSEMBL:ENSMUSG00000024810
UNIPROT:Q8BVZ5
Basic Information
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Transcripts
Exons
Length
MW (kDa)
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Reference
77125
5
8
35606 bp
29.99
23
10
Il33 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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