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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Slc9a8 - solute carrier family 9 (sodium/hydrogen exchanger), member 8
Alias:
NHE8
NHE-8
1200006P13Rik
6430709P13Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
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References Literature
这个基因编码Na+/H+交换子(NHE)家族的一员,这是一类整合膜转运蛋白。编码的蛋白质在肠道上皮细胞的顶膜上表达,并在黏膜保护中扮演重要角色。小鼠中编码蛋白质的缺失导致杯状细胞数量和粘蛋白阳性细胞的减少,粘蛋白层的紊乱,以及结肠黏膜pH值的降低。这个基因的可变剪接导致多个转录子变异。[由RefSeq,2015年1月提供]
Related ID:
NCBI:77031
ENSEMBL:ENSMUSG00000039463
UNIPROT:Q8R4D1
Basic Information
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Transcripts
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MW (kDa)
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77031
12
17
57243 bp
64.74
10
16
Slc9a8 Genetics information (+)
GRCm39
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* This data comes from NCBI.
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