小鼠

Arfrp1 - ADP-ribosylation factor related protein 1

Alias:
1500006I01Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
该基因编码一个与ADP-核糖基化因子(ARF)和ARF样(ARL)基因相关的膜关联GTP酶。它在高尔基体功能中扮演重要角色,控制GRIP结构域蛋白质和ARL1招募到跨高尔基体以及细胞表面蛋白质如E-钙粘着蛋白从高尔基体到质膜的转运。在小鼠中删除该基因会导致在早期胃胚形成期间的胚胎致死,这至少部分是由于E-钙粘附蛋白向细胞表面的转运受阻,从而在胚胎中缺乏足够的细胞间粘附。已发现该基因有多个转录变异体,编码不同的异构体。[RefSeq,2009年10月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
4
8
7715 bp
22.66
3
10

Arfrp1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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