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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Arfrp1 - ADP-ribosylation factor related protein 1
Alias:
1500006I01Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
该基因编码一个与ADP-核糖基化因子(ARF)和ARF样(ARL)基因相关的膜关联GTP酶。它在高尔基体功能中扮演重要角色,控制GRIP结构域蛋白质和ARL1招募到跨高尔基体以及细胞表面蛋白质如E-钙粘着蛋白从高尔基体到质膜的转运。在小鼠中删除该基因会导致在早期胃胚形成期间的胚胎致死,这至少部分是由于E-钙粘附蛋白向细胞表面的转运受阻,从而在胚胎中缺乏足够的细胞间粘附。已发现该基因有多个转录变异体,编码不同的异构体。[RefSeq,2009年10月提供]
Related ID:
NCBI:76688
ENSEMBL:ENSMUSG00000038671
UNIPROT:Q8BXL7
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
76688
4
8
7715 bp
22.66
3
10
Arfrp1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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