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Arhgap15 - Rho GTPase activating protein 15

Alias:
5830480G12Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一个通过其PH结构域和招募到膜上而受到调节的RAC GTP酶激活蛋白。该蛋白质加速了三磷酸鸟苷到二磷酸鸟苷的水解,从而抑制Rac的活性。Arhgap15功能的敲除表明,这个基因在调节巨噬细胞和中性粒细胞中的多个功能是必需的。可选的剪接导致了编码不同异型体的多种转录变异体。[由RefSeq,2014年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
9
14
647180 bp
55.34
4
5

Arhgap15 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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