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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Arhgap15 - Rho GTPase activating protein 15
Alias:
5830480G12Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一个通过其PH结构域和招募到膜上而受到调节的RAC GTP酶激活蛋白。该蛋白质加速了三磷酸鸟苷到二磷酸鸟苷的水解,从而抑制Rac的活性。Arhgap15功能的敲除表明,这个基因在调节巨噬细胞和中性粒细胞中的多个功能是必需的。可选的剪接导致了编码不同异型体的多种转录变异体。[由RefSeq,2014年9月提供]
Related ID:
NCBI:76117
ENSEMBL:ENSMUSG00000049744
UNIPROT:Q811M1
Basic Information
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Transcripts
Exons
Length
MW (kDa)
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Reference
76117
9
14
647180 bp
55.34
4
5
Arhgap15 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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