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中文小鼠
Dock8 - dedicator of cytokinesis 8
Alias:
1200017A24Rik
5830472H07Rik
A130095G14Rik
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激活鸟苷酸交换因子活性。参与树突状细胞迁移；正调节T细胞迁移；以及正调节T细胞极性建立。在免疫学突触形成和T细胞凋亡过程的负调节中起到上游或内部作用。位于细胞前沿。在中枢神经系统、视网膜和胸腺原基中表达。该基因的人类同源物与特应性皮炎、细菌性传染病、高IgE复发感染综合征2、免疫失调-多内分泌病-肠病-X-连锁综合征和病毒性传染病（多种）有关。与人类DOCK8（细胞分裂指示蛋白8）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Dock8 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
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MGI
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