人类

ZFX - Zinc Finger Protein X-linked

Alias:
ZNF926
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个位于X染色体上的基因在结构上与Y染色体上的相关基因相似。它编码一个krueppel C2H2型锌指蛋白家族的成员。全长蛋白质包含一个酸性转录激活结构域(AD),一个核定位序列(NLS)和一个由13个C2H2型锌指组成的DNA结合结构域(DBD)。在小鼠胚胎和成年造血干细胞的研究中表明,这个基因作为两种干细胞类型的自我更新的转录调节因子是必需的,但对于它们的子代的生长和分化是非必需的。已经识别出多种可变剪接转录变异体,编码不同的异构体,但某些变异体的全长性质尚未确定。[RefSeq,2010年5月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
52
10
67274 bp
90.52
14
--
3
7

ZFX Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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