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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Kmt2b - lysine (K)-specific methyltransferase 2B
Alias:
Mll2
Wbp7
mKIAA0304
2610014H22Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够激活组蛋白甲基转移酶活性(特异性的H3-K4);未甲基化的CpG结合活性;和锌离子结合活性。在几个过程的上游或内部发挥作用,包括DNA甲基化依赖的异染色质组装;雌性配子的生成;和组蛋白H3-K4的三甲基化。预测位于细胞核中。预测是组蛋白甲基转移酶复合物的一部分。在几个结构中表达,包括消化系统;内细胞团;神经系统;感觉器官;和泌尿系统。这个基因的人类正集(s)与结直肠癌;肌张力障碍;和肝细胞癌有关。与人类KMT2B(赖氨酸甲基转移酶2B)正集同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:75410
ENSEMBL:ENSMUSG00000006307
UNIPROT:O08550
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
75410
6
37
20092 bp
294.82
8
6
Kmt2b Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
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