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中文人类
SF1 - Splicing Factor 1
Alias:
BBP
MBBP
ZFM1
ZNF162
D11S636
ZCCHC25
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这个基因编码一个核前mRNA剪接因子。编码的蛋白质特异性地识别3'剪接位点的内含子分支点序列，与U2辅助因子（U2AF）的大亚基一起，并在剪接体组装的早期阶段是必需的。它还在核前mRNA保留和转录抑制中发挥作用。编码的蛋白质包含一个N-末端U2AF配体基序，一个结合分支点序列内关键分支腺苷的中央hnRNP K同源基序和quaking 2区域，一个锌指结构域，和一个C-末端富含脯氨酸的结构域。可变剪接产生多种转录变异体。[由RefSeq，2016年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SF1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
