人类

YWHAZ - Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein Zeta

Alias:
HEL4
YWHAD
KCIP-1
HEL-S-3
POPCHAS
HEL-S-93
14-3-3-zeta
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因产物属于14-3-3家族蛋白质,通过结合含有磷酸丝氨酸的蛋白质来调节信号传导。这个高度保守的蛋白质家族在植物和哺乳动物中都有发现,这个蛋白质与小鼠、大鼠和羊的同源物有99%的相同性。编码的蛋白质与IRS1蛋白质相互作用,提示在调节胰岛素敏感性中起作用。已经在这个基因中鉴定出几个在5'UTR不同但编码相同蛋白质的转录变异体。[由RefSeq,2008年10月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10
6
36860 bp
27.75
22
1
7
51

YWHAZ Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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