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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
YWHAZ - Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein Zeta
Alias:
HEL4
YWHAD
KCIP-1
HEL-S-3
POPCHAS
HEL-S-93
14-3-3-zeta
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因产物属于14-3-3家族蛋白质,通过结合含有磷酸丝氨酸的蛋白质来调节信号传导。这个高度保守的蛋白质家族在植物和哺乳动物中都有发现,这个蛋白质与小鼠、大鼠和羊的同源物有99%的相同性。编码的蛋白质与IRS1蛋白质相互作用,提示在调节胰岛素敏感性中起作用。已经在这个基因中鉴定出几个在5'UTR不同但编码相同蛋白质的转录变异体。[由RefSeq,2008年10月提供]
Related ID:
NCBI:7534
ENSEMBL:ENSG00000164924
HGNC:12855
UNIPROT:P63104
OMIM:601288
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7534
10
6
36860 bp
27.75
22
1
7
51
YWHAZ Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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Status
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