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中文人类
XRCC1 - X-ray Repair Cross Complementing 1
Alias:
RCC
SCAR26
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这个基因编码的蛋白质参与对电离辐射和烷基化剂形成的DNA单链断裂的高效修复。这个蛋白质与DNA连接酶III、聚合酶beta和多(ADP-核糖)聚合酶相互作用，参与碱基切除修复途径。它可能在减数分裂期间的DNA处理和在生殖细胞的重组中发挥作用。这个基因中的罕见微卫星多态性与不同放射敏感性的患者的癌症相关。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
XRCC1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
