人类

WNT5A - Wnt Family Member 5A

Alias:
hWNT5A
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
WNT基因家族由结构相关的基因组成,这些基因编码分泌的信号蛋白。这些蛋白与癌症发生和几个发育过程有关,包括胚胎发育期间细胞命运和模式的调控。这个基因编码一个通过经典和非经典WNT途径信号的WNT家族成员。这个蛋白是七跨膜受体frizzled-5和酪氨酸激酶孤儿受体2的配体。这个蛋白在胚胎发育期间调控发育途径中起基本作用。这个蛋白也可能在癌症发生中起作用。这个基因的突变是导致常染色体显性Robinow综合征的原因。交替剪接导致多个转录变异体。[由RefSeq,2012年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
20
5
39549 bp
42.34
179
3
8
11

WNT5A Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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