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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
WNT5A - Wnt Family Member 5A
Alias:
hWNT5A
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
WNT基因家族由结构相关的基因组成,这些基因编码分泌的信号蛋白。这些蛋白与癌症发生和几个发育过程有关,包括胚胎发育期间细胞命运和模式的调控。这个基因编码一个通过经典和非经典WNT途径信号的WNT家族成员。这个蛋白是七跨膜受体frizzled-5和酪氨酸激酶孤儿受体2的配体。这个蛋白在胚胎发育期间调控发育途径中起基本作用。这个蛋白也可能在癌症发生中起作用。这个基因的突变是导致常染色体显性Robinow综合征的原因。交替剪接导致多个转录变异体。[由RefSeq,2012年1月提供]
Related ID:
NCBI:7474
ENSEMBL:ENSG00000114251
HGNC:12784
UNIPROT:P41221
OMIM:164975
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7474
20
5
39549 bp
42.34
179
3
8
11
WNT5A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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