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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
WARS1 - Tryptophanyl-tRNA Synthetase 1
Alias:
HMN9
WARS
IFI53
IFP53
GAMMA-2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
氨基酸-tRNA合成酶通过其相应的氨基酸催化tRNA的氨基酸化。由于它们在将氨基酸与tRNA中的核苷酸三联体连接起来的核心作用,氨基酸-tRNA合成酶被认为是进化中最早出现的蛋白质之一。色氨酸-tRNA合成酶有两种形式,一种为胞质形式,名为WARS,另一种为线粒体形式,名为WARS2。色氨酸-tRNA合成酶(WARS)催化tRNA(trp)与色氨酸的氨基酸化,并被干扰素诱导。色氨酸-tRNA合成酶属于I类tRNA合成酶家族。已发现此基因编码两种不同异构体的四种转录变异体。[RefSeq,2008年7月提供]
Related ID:
NCBI:7453
ENSEMBL:ENSG00000140105
HGNC:12729
UNIPROT:P23381
OMIM:191050
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7453
16
11
42538 bp
53.16
51
5
4
33
WARS1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Name
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CAS Number
Status
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References Literature
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