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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MYRF - Myelin Regulatory Factor
Alias:
MRF
CUGS
MMERV
Ndt80
11orf9
pqn-47
C11orf9
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个转录因子,是中枢神经系统髓鞘形成所必需的,并可能调节少突胶质细胞分化。它被认为通过增加影响髓鞘产生的基因表达来发挥作用,但也可能直接促进髓鞘基因的表达。在类似基因缺失的小鼠模型中,会导致严重的脱髓鞘。可变剪接导致多个转录本变异。[由RefSeq,2014年11月提供]
Related ID:
NCBI:745
ENSEMBL:ENSG00000124920
HGNC:1181
UNIPROT:Q9Y2G1
OMIM:608329
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
745
24
27
35883 bp
124.40
144
3
7
11
MYRF Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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