Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
VASP - Vasodilator Stimulated Phosphoprotein
新建收藏夹
取消
确认
加入收藏夹
选择一个收藏夹
描述信息
新收藏夹 >>
取消
确认
加入收藏
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
VASP(Vasodilator-stimulated phosphoprotein)是Ena-VASP蛋白家族的成员。Ena-VASP家族成员含有EHV1 N-末端结构域,可以结合含有E/DFPPPPXD/E基序的蛋白质,并将Ena-VASP蛋白靶向至粘着斑。在蛋白质的中部区域,家族成员具有一个富含脯氨酸的结构域,可以结合SH3和WW结构域富含的蛋白质。它们的C-末端EVH2结构域可以介导四聚化,并结合G和F肌动蛋白。VASP与丝状肌动蛋白形成有关,可能在细胞粘附和迁移中扮演广泛的角色。VASP可能还涉及调节整合素-细胞外基质相互作用的细胞内信号通路。VASP受到环核苷酸依赖性激酶PKA和PKG的调节。[由RefSeq,2008年7月提供]
Related ID:
NCBI:7408
ENSEMBL:ENSG00000125753
HGNC:12652
UNIPROT:P50552
OMIM:601703
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7408
4
13
19505 bp
39.83
22
--
4
39
VASP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top