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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Als2 - alsin Rho guanine nucleotide exchange factor
Alias:
Alsin
Als2cr6
mKIAA1563
3222402C23Rik
9430073A21Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能激活多种功能,包括GTP酶调节活性;蛋白质同二聚体活性;和小GTP酶结合活性。在几个过程的上游或内部发挥作用,包括行为恐惧反应;谷氨酸能突触传递;和受体回收。位于几个细胞组件中,包括中心体;膜瓣;和ruffle。在几个结构中表达,包括中枢神经系统;泌尿系统;血细胞系统;肝脏;和视网膜。该基因的人类同源物与肌萎缩侧索硬化症和肌萎缩侧索硬化症2型有关。与人类ALS2(ALS2 Rho鸟苷酸交换因子)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:74018
ENSEMBL:ENSMUSG00000026024
UNIPROT:Q920R0
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
74018
3
34
74476 bp
182.57
9
8
Als2 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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