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Irak3 - interleukin-1 receptor-associated kinase 3

Alias:
IRAK-M
4833428C18Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活ATP结合活性;镁离子结合活性;以及蛋白质丝氨酸/苏氨酸激酶活性。参与几个过程,包括大分子代谢过程的负调控;巨噬细胞耐受诱导的正调控;以及响应细菌来源的分子的反应。在白细胞介素-1介导的信号通路的上游或内部发挥作用;NF-kappaB转录因子活性的正调控;以及蛋白质自磷酸化。位于细胞质和核中。用于研究骨质疏松症和1型糖尿病。该基因的人类同源物与哮喘有关。与人类IRAK3(白细胞介素1受体相关激酶3)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
12
60483 bp
68.45
9
5

Irak3 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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