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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Irak3 - interleukin-1 receptor-associated kinase 3
Alias:
IRAK-M
4833428C18Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活ATP结合活性;镁离子结合活性;以及蛋白质丝氨酸/苏氨酸激酶活性。参与几个过程,包括大分子代谢过程的负调控;巨噬细胞耐受诱导的正调控;以及响应细菌来源的分子的反应。在白细胞介素-1介导的信号通路的上游或内部发挥作用;NF-kappaB转录因子活性的正调控;以及蛋白质自磷酸化。位于细胞质和核中。用于研究骨质疏松症和1型糖尿病。该基因的人类同源物与哮喘有关。与人类IRAK3(白细胞介素1受体相关激酶3)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:73914
ENSEMBL:ENSMUSG00000020227
UNIPROT:Q8K4B2
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
73914
2
12
60483 bp
68.45
9
5
Irak3 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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