人类

UNG - Uracil DNA Glycosylase

Alias:
DGU
UDG
UNG1
UNG2
HIGM4
HIGM5
UNG15
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码几种尿嘧啶-DNA糖基化酶中的一种。尿嘧啶-DNA糖基化酶的一个重要功能是通过切割N-糖苷键并从DNA分子中消除尿嘧啶来防止突变。尿嘧啶碱基是由胞嘧啶脱氨或dUMP残基的错配产生的。这个基因的替代启动子使用和剪接导致两种不同的异构体:线粒体UNG1和核UNG2。在文献和一些数据库中,UNG2被用作CCNO基因(GeneID 10309)的前一个符号,这与其他基因发生了混淆。[RefSeq, 2010年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
7
13396 bp
34.65
240
1
5
26

UNG Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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