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中文人类
UCP2 - Uncoupling Protein 2
Alias:
UCPH
BMIQ4
SLC25A8
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线粒体解耦联蛋白（UCP）是更大的线粒体阴离子载体蛋白（MACP）家族的成员。UCP将氧化磷酸化与ATP合成分开，能量以热量形式消散，也称为线粒体质子泄漏。UCP促进阴离子从内质网膜到外质网膜的转移，以及质子从外质网膜到内质网膜的返回转移。它们还可以降低哺乳动物细胞中的线粒体膜电位。不同UCP的组织特异性及其转移H+/OH-的确切方法尚不清楚。UCP包含MACP的三个同源蛋白质结构域。该基因在许多组织中表达，以骨骼肌中的表达最强。认为它在非寒战产热、肥胖和糖尿病中起作用。染色体顺序是5'-UCP3-UCP2-3'。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
UCP2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
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Residues
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Score
Related Mouse Models
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Name
MGI
Strain of Origin
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References Literature
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