人类

UCP1 - Uncoupling Protein 1

Alias:
UCP
SLC25A7
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
线粒体解耦联蛋白(UCP)是线粒体阴离子载体蛋白(MACP)家族的成员。UCP将氧化磷酸化与ATP合成分开,将能量以热的形式耗散,也称为线粒体质子泄漏。UCP促进阴离子从内质网膜到外质网膜的转移,以及质子从外质网膜到内质网膜的返回转移。它们还可以降低哺乳动物细胞中的线粒体膜电位。不同UCP的组织特异性及其转移H+/OH-的确切方法尚不清楚。UCP包含MACP的三个同源蛋白质结构域。此基因仅在专门产生热量的棕色脂肪组织中表达。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
6
9531 bp
33.01
21
--
21
9

UCP1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
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