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中文人类
UBE2L3 - Ubiquitin Conjugating Enzyme E2 L3
Alias:
E2-F1
L-UBC
UBCH7
UbcM4
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泛素化是细胞内一种重要的蛋白质修饰机制，用于靶向异常或短寿命蛋白质进行降解。泛素化涉及至少三类酶：泛素-活化酶（E1s），泛素-结合酶（E2s）和泛素-蛋白连接酶（E3s）。这个基因编码一个E2泛素-结合酶家族的成员。这个酶已被证明参与体外p53，c-Fos和NF-kB前体p105的泛素化。已发现该基因有几个可变剪接转录变异体。[RefSeq，2009年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
UBE2L3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
