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中文人类
UBA7 - Ubiquitin Like Modifier Activating Enzyme 7
Alias:
D8
UBE2
UBE7
UBA1B
UBE1L
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泛素化是一种重要的细胞机制，用于将异常或短寿命的蛋白质靶向降解。泛素化涉及至少三类酶：泛素-活化酶（E1），泛素-结合酶（E2）和泛素-蛋白连接酶（E3）。这个基因编码一个E1泛素活化酶家族的成员。编码的酶是类视黄醇靶标，能触发急性早幼粒细胞白血病（PML）/视黄酸受体α（RARα）降解和凋亡，参与泛素样干扰素刺激基因15蛋白的连接。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
UBA7 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
