Predicted to enable oxysterol binding activity. Acts upstream of or within several processes, including cholesterol biosynthetic process; ear morphogenesis; and negative regulation of lipid biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of SREBP-SCAP-Insig complex. Predicted to be active in endoplasmic reticulum. Is expressed in central nervous system; jaw bone; and retina. Orthologous to human INSIG2 (insulin induced gene 2). [provided by Alliance of Genome Resources, Apr 2022]