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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Appl1 - adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Alias:
DIP13
2900057D21Rik
7330406P05Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够实现几个功能,包括β-微管蛋白结合活性;磷脂结合活性;和蛋白质同二聚体化活性。参与几个过程,包括肝细胞生长因子刺激的细胞响应;参与炎性反应的细胞因子产生的正向调节;以及调节囊泡介导的运输。位于胞质囊泡和ruffle。在几个结构中表达,包括肝脏;肌肉组织;脾脏;胃;和睾丸。这个基因的人类同源物与青年型糖尿病14型有关。与人类APPL1(适配器蛋白,与PH结构域和亮氨酸扎染器1相互作用的磷酸酪氨酸)的同源物。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:72993
ENSEMBL:ENSMUSG00000040760
UNIPROT:Q8K3H0
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
72993
4
22
51625 bp
79.33
7
13
Appl1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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