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中文人类
TNFRSF4 - TNF Receptor Superfamily Member 4
Alias:
OX40
ACT35
CD134
IMD16
TXGP1L
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这个基因编码的蛋白质是肿瘤坏死因子受体超家族的一员。这个受体通过与适应蛋白TRAF2和TRAF5的相互作用激活NF-kappaB。在小鼠中进行的敲除研究表明，这个受体促进抗凋亡抑制剂BCL2和BCL2lL1/BCL2-XL的表达，从而抑制凋亡。敲除研究还表明了这个受体在CD4+T细胞反应，以及在T细胞依赖的B细胞增殖和分化中的作用。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TNFRSF4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
