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中文人类
CCR2 - C-C Motif Chemokine Receptor 2
Alias:
CKR2
CCR-2
CCR2A
CCR2B
CD192
CKR2A
CKR2B
CMKBR2
MCP-1-R
CC-CKR-2
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这个基因编码的蛋白质是一种单核细胞趋化蛋白-1受体，这是一种专门调节单核细胞趋化的化学因子。单核细胞趋化蛋白-1涉及炎症性疾病如类风湿关节炎中的单核细胞浸润，以及针对肿瘤的炎症反应。编码的蛋白质调节激动剂依赖的钙动员和腺苷酸环化酶的抑制。这种蛋白质还可以作为HIV-1感染的CD4共受体。这个基因位于染色体3的化学因子受体基因簇区域。[RefSeq，2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CCR2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
