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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CDK11A - Cyclin Dependent Kinase 11A
Alias:
CDC2L2
CDC2L3
p58GTA
PITSLRE
CDK11-p46
CDK11-p58
CDK11-p110
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码丝氨酸/苏氨酸蛋白激酶家族的一个成员。这个激酶家族的成员被认为是真核细胞周期调控所必需的。由于一段重复,这个基因与邻近的一个基因有非常高的序列同源性。这两个基因在神经母细胞瘤中经常被删除或改变。这个基因编码的蛋白激酶可以被半胱氨酸蛋白酶裂解,可能在细胞凋亡中发挥作用。不同的剪接方式导致了多种转录变体。[由RefSeq提供,2015年9月]
Related ID:
NCBI:728642
ENSEMBL:ENSG00000008128
HGNC:1730
UNIPROT:Q9UQ88
OMIM:116951
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
728642
4
20
21979 bp
91.36
39
--
4
7
CDK11A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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References Literature
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