Log In|Sign Up
中文人类
TSG101 - Tumor Susceptibility 101
Alias:
TSG10
VPS23
Favorite
这个基因编码的蛋白质属于泛素结合酶的似乎无活性的同系物组。基因产物包含与细胞质磷酸蛋白 stathmin 相互作用的螺旋卷域，stathmin 与肿瘤发生有关。该蛋白质可能在细胞生长和分化中发挥作用，并作为负生长调节剂。在体外，这个肿瘤易感基因的稳态表达对于维持基因组稳定性和细胞周期调节可能很重要。这个基因中的突变和替代剪接在乳腺癌中高频发生，提示在乳腺癌发生和/或进展过程中存在缺陷。[由 RefSeq，2008 年 7 月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TSG101 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
