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中文人类
TSN - Translin
Alias:
C3PO
RCHF1
TBRBP
TRSLN
BCLF-1
REHF-1
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这个基因编码一种DNA结合蛋白，该蛋白能特异性识别染色体易位断裂接头处保守靶序列。Translin多肽形成一个多聚体结构，负责其DNA结合活性。重组相关模式和Translin结合位点存在于重组热点中，可能是通过易位融合的基因的断点的指示器。这些结合活性在淋巴瘤染色体易位中可能起着关键作用。这个基因编码的蛋白质，当与Translin相关蛋白X复合时，也形成一种依赖于Mg离子的内切核酸酶，促进RNA诱导的沉默复合物（RISC）激活。选择性剪接导致多种转录变体。[由RefSeq提供，2012年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TSN Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
