Brap - BRCA1 associated protein

Predicted to enable identical protein binding activity; nuclear localization sequence binding activity; and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of signal transduction. Predicted to act upstream of or within MAPK cascade; Ras protein signal transduction; and protein ubiquitination. Predicted to be located in cytosol; nuclear membrane; and nucleoplasm. Predicted to be part of ubiquitin ligase complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; retina; and vibrissa. Orthologous to human BRAP (BRCA1 associated protein). [provided by Alliance of Genome Resources, Apr 2022]