Lrrc8e - leucine rich repeat containing 8 family, member E

Predicted to contribute to volume-sensitive anion channel activity. Involved in cyclic-GMP-AMP transmembrane import across plasma membrane. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of endoplasmic reticulum membrane; integral component of lysosomal membrane; and integral component of plasma membrane. Predicted to be part of ion channel complex. Orthologous to human LRRC8E (leucine rich repeat containing 8 VRAC subunit E). [provided by Alliance of Genome Resources, Apr 2022]