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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TRPC5 - Transient Receptor Potential Cation Channel Subfamily C Member 5
Alias:
TRP5
PPP1R159
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因属于瞬时受体家族。它编码七种哺乳动物TRPC(瞬时受体潜在通道)蛋白质之一。编码的蛋白质是一种多通道膜蛋白,被认为可以形成受体激活的非选择性钙通透阳离子通道。该蛋白质可以单独发挥作用,也可以与TRPC1、TRPC3和TRPC4组成异源多聚体。它还可以与多种蛋白质相互作用,包括钙调素、CABP1、enkurin、Na+-H+交换调节因子(NHERF)、干扰素诱导的GTP结合蛋白(MX1)、环指蛋白24(RNF24)和包含SEC14结构域和谱系重复的蛋白质1(SESTD1)。[RefSeq提供,2010年5月]
Related ID:
NCBI:7224
ENSEMBL:ENSG00000072315
HGNC:12337
UNIPROT:Q9UL62
OMIM:300334
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
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Reference
7224
3
11
314766 bp
111.41
34
--
14
12
TRPC5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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