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中文人类
NR2C2 - Nuclear Receptor Subfamily 2 Group C Member 2
Alias:
TR4
TAK1
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这个基因编码一个属于核激素受体家族的蛋白质。这个家族的成员作为配体激活的转录因子，并在许多生物过程中发挥作用，如发育、细胞分化和体内平衡。激活的受体/配体复合物被转移到核中，在那里它结合到目标基因的激素响应元素上。这个基因编码的蛋白质在保护细胞免受氧化应激和电离辐射诱导的损伤中发挥作用。在老鼠中缺乏类似的基因会导致生长迟缓、严重的脊柱弯曲、次级不育、过早衰老和前列腺上皮内瘤(PIN)的发展。可选的剪接导致编码不同异型体的多种转录变异体。[由RefSeq，2014年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NR2C2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
