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中文人类
TPT1 - Tumor Protein, Translationally-controlled 1
Alias:
HRF
p02
p23
TCTP
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这个基因编码一种调控细胞生长和增殖的蛋白质。其mRNA高度结构化，并在其5'非翻译区含有寡嘧啶区（5'-TOP），在静息条件下具有抑制其翻译的功能。编码的蛋白质涉及多种细胞途径，包括凋亡、蛋白质合成和细胞分裂。它结合并稳定微管，通过磷酸化去除此蛋白质是有丝分裂和减数分裂细胞分裂进程所必需的。已知此基因在癌症发生中起作用，并在某些癌细胞中上调。选择性剪接产生多种转录变异体，编码不同的异构体。[RefSeq，2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TPT1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
