Log In|Sign Up
中文小鼠
Marchf8 - membrane associated ring-CH-type finger 8
Alias:
Mir
March8
MARCH-VIII
1300017E09Rik
Favorite
这个基因编码的蛋白质是膜关联的真的很有趣的新基因-CH家族蛋白质的一员。这些蛋白质作为E3泛素蛋白连接酶，通过内吞作用下调主要组织相容性复合体II类表面表达，从而调节抗原呈递。该转录本主要由树突状细胞和巨噬细胞表达。在抗原呈递细胞中过度表达该基因会导致免疫缺陷表型，包括对自身免疫疾病发作的抵抗力增加。可变剪接导致多个转录变异体。[由RefSeq，2014年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Marchf8 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
