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中文人类
TPO - Thyroid Peroxidase
Alias:
MSA
TPX
TDH2A
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这个基因编码一个膜结合糖蛋白。编码的蛋白质作为酶，在甲状腺腺体功能中扮演重要角色。该蛋白质在甲状腺球蛋白中的酪氨酸残基碘化以及在生成甲状腺激素T4和T3的过程中，成对的碘化酪氨酸之间形成苯氧酯。这个基因的突变与几种甲状腺激素生成障碍有关，包括先天性甲状腺功能减退、先天性甲状腺肿大和甲状腺激素器官化缺陷IIA。已经发现了这个基因的多个转录变异体，编码不同的异构体，但某些变异体的完整长度尚未确定。[由RefSeq提供，2011年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TPO Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
