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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TPM4 - Tropomyosin 4
Alias:
HEL-S-108
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Description
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码肌动蛋白结合蛋白中的肌球蛋白家族成员,参与横纹肌和平滑肌的收缩系统以及非肌肉细胞的细胞骨架。肌球蛋白是端对端沿着大部分肌动蛋白丝的主要沟槽聚合的螺旋蛋白二聚体。它们为丝状物提供稳定性,并调节其他肌动蛋白结合蛋白的访问。在肌肉细胞中,它们通过控制肌球蛋白头与肌动蛋白丝的结合来调节肌肉收缩。已发现这个基因的不同转录变异体编码不同的异构体。[RefSeq,2009年11月提供]
Related ID:
NCBI:7171
ENSEMBL:ENSG00000167460
HGNC:12013
UNIPROT:P67936
OMIM:600317
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7171
5
8
35465 bp
28.52
12
3
5
15
TPM4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Regulation
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Reference
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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